API Intermediates

 

 

CAS NO.

 

 
非奈利酮
Finerenone		  

 

1050477-31-0

 
4-formyl-3-methoxybenzonitrile

 

21962-45-8

 
4-Amino-2-hydroxy-5-methylpyridine

 

95306-64-2

 
2-Cyanoethyl 3-oxobutanoate

 

65193-87-5

 
2-chloro-5-methylpyridin-4-amine

 

79055-62-2

 
　 intermediate N-3

 

1050477-43-4

 
　 　 　
奥西替尼
Osimertinib		  

 

1421373-65-0

 
3-(2-chloropyriMidin-4-yl)-1-Methylindole

 

1032452-86-0

 
4-fluoro-2-Methoxy-5-nitroaniline

 

1075705-01-9

 
N,N,N'-Trimethylethylenediamine

 

142-25-6

 
AZD9291intermediate 2

 

1421372-94-2

 
Osimertinib mesylate

 

1421373-66-1

 
AZD9291 intermediate 3

 

1421372-67-9

 
AZD9291intermediate 1 1421372-66-8
　 　 　
瑞司美替罗
Resmetirom		  

 

920509‑32‑6

 
(Z)-ethyl (2-cyano-2-(2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)hydrazono)acetyl)carbamate(WXG00198)

 

920509-33-7

 
6-(4-Amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one

 

920509-28-0

 
 3,5-dichloro-4-((6-chloro-5-isopropylpyridazin-3-yl)oxy)aniline(WXG00196)

 

920509-27-9

 
乌帕替尼
Upadacitinib		  

 

1310726-60-3

​
(3R,4S)-4-ethylpyrrolidine-3-carboxylic acid

 

1821826-28-1

 
intermediate N-3

 

2050038-81-6

 
intermediate N-1

 

2050038-84-9

 
苏泽曲林
Suzetrigine		  

 

2649467-58-1

 
3,4-Difluoro-2-methoxyphenylacetic acid

 

1558274-26-2

 
(R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid

 

44864-47-3

 
Methyl 4-aminopyridine-2-carboxylate

 

71469-93-7

 
(R)-4,4,4-Trifluoro-3-hydroxy-3-methylbutan-2-one

 

2875067-31-3

 
(R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)furan-2(5H)-one

 

2875066-35-4

 
艾拉司群
Elacestrant		  

 

722533-56-4

 
N-(2-(6-(benzyloxy)-3,4-dihydronaphthalen-2-yl)-5-methoxyphenyl)acetamide

 

2477812-37-4

 
(6R)-6-(2-amino-4-methoxyphenyl)-5,6,7,8-tetrahydro-2-Naphthalenol

 

2477812-39-6

 
奥格列龙
Orforglipron		  

 

2212020-52-3

 
(2S)-tert-Butyl 3-cyano-2-methyl-4-oxopiperidine-1-carboxylate

 

2212021-56-0

 
(4-Fluoro-3,5-dimethylphenyl)hydrazine hydrochloride

 

2212021-40-2

 
tert-butyl (S)-3-amino-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate

 

2212021-59-3

 
N-(2,2-dimethoxyethyl)-1H-imidazole-1-carboxamide

 

183660-46-0

 
5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 3-[[[(2,2-dimethoxyethyl)amino]carbonyl]amino]-2-(4-fluoro-3,5-dimethylphenyl)-2,4,6,7-tetrahydro-4-methyl-, 1,1-dimethylethyl ester, (4S)- 2212021-60-6
5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 3-(2,3-dihydro-2-oxo-1H-imidazol-1-yl)-2-(4-fluoro-3,5-dimethylphenyl)-2,4,6,7-tetrahydro-4-methyl-, 1,1-dimethylethyl ester, (4S)- 2212021-61-7
5-Bromo-4-fluoro-1-methyl-1H-indazole

 

1784678-61-0

 
(S)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1H-imidazol-2(3H)-one

 

2212022-56-3

 
1H-Indole-2-carboxylic acid, 5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-

 

2212021-78-6

 
1H-Indole-2-carboxamide, N-methyl-N-phenyl-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-

 

2212021-79-7

 
1,3,2-Dioxathiolane, 4-Methyl-, 2,2-dioxide, (4R)-

 

1006381-03-8